Bimatoprost 0.03%/timolol 0.5% preservative

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As topical medications are normally dispensed from multiuse bottles, preservative (typically benzalkonium chloride, BAK) is employed to maintain sterility. Although many patients use preservative containing medications without adverse effects,10 11 some become sensitive to ophthalmic preservatives.12 13 A single-dose, preservative-free (PF) ophthalmic fixed combination would benefit this patient subpopulation.

Our study evaluated the safety and efficacy of a new PF fixed-combination bimatoprost 0.03%/timolol 0.5% (bimatoprost/timolol PF; Ganfort SD) for patients who are sensitive or allergic to preservatives.

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